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Administering immunotherapy in the morning seems to matter. Why?
3k words, 14 minutes reading time
Top posts
Every blog post that took off on Hacker News, ranked by the votes of its best submission. 422 posts.
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It's hard to build an oscillator
Especially if you want it to work.
153
Magpies and crows are using “anti-bird spikes” to make nests (2023)
Birds often incorporate human-made materials while nest building, but a new study shows European corvids are taking the idea to the extreme.
154
Where does air pollution come from?
A breakdown of the sources of many air pollutants that damage our health and ecosystems.
155
Why you can't color calibrate deep space photos
Color is the most disputed part of astrophotography: Every image looks different and the internet is full of arguments over what colors are correct or natural.
156
Progress toward fusion energy gain as measured against the Lawson criteria
Today we’ve released a pre-publication version of an update to our 2022 paper “Progress toward fusion energy breakeven and gain as measured against the...
157
Does X cause Y? An in-depth evidence review (2021)
This summarizes the frustratingly ambiguous state of the evidence for pretty much any "Does X cause Y?" question you might have.
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CubeSats are fascinating learning tools for space
These are CubeSats. Satellites that are going to space—or at least, the ones I have here are prototypes. But these have one thing in common: they're all powered by either a Raspberry Pi, or a microcontroller. There are already Pis in space, like on Mark Rober's SatGus, on GASPACS, and the Astro Pis on the Space…
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Modification of acetaminophen to reduce liver toxicity and enhance drug efficacy
2025 Science Talent Search Project Showcase: Chloe Yehwon Lee, 17, of Murphy, explored a way to lower the toxic effects of acetaminophen (Tylenol) on the liver for her Regeneron Science Talent Search chemistry project.
161
Oxygen atoms discovered in most distant known galaxy
Two different teams of astronomers have detected oxygen in the most distant known galaxy, JADES-GS-z14-0. The discovery, reported in two separate studies, was made possible thanks to the Atacama Large Millimeter/submillimeter Array (ALMA), in which the European Southern Observatory (ESO) is a partner. This…
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When Abandoned Mines Collapse
[Note that this article is a transcript of the video embedded above.] In December of 2024, a huge sinkhole opened up on I-80 near Wharton, New Jersey, creating massive traffic delays as crews worked to figure out what happened and get it fixed. Since then, it happened again in February 2025 and th
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More honey bees dying, even as antibiotic use halves
Despite tighter restrictions on antibiotics used in Canadian beekeeping, honey bee death rates are still rising. A new study led by University of Guelph researchers, published in Nature Sustainability…
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New protein therapy shows promise as antidote for carbon monoxide poisoning
Established in 1807, we are the fifth oldest medical school in the United States and the first in the country to institute a residency training program.
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It doesn't cost much to improve someone's life
Most countries spend less than 1% of their national income on foreign aid; even small increases could make a big difference.
166
New studies offer insight into Lyme disease’s treatment, lingering symptoms
In two new studies led by bacteriologist Brandon L. Jutras, Northwestern scientists have identified an antibiotic that cures Lyme disease at a fraction of the dosage of the current “gold standard” treatment and discovered what may cause a treated infection to mimic chronic illness in patients.
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A Gemma model helped discover a new potential cancer therapy pathway
We’re launching a new 27 billion parameter foundation model for single-cell analysis built on the Gemma family of open models.
168
Researchers discover molecular difference in autistic brains
Brains of autistic individuals have fewer of a specific kind of glutamate receptor, supporting an idea that autism is driven by a signaling imbalance. The
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American solar farms
Benchmarks & Tips for Big Data, Hadoop, AWS, Google Cloud, PostgreSQL, Spark, Python & More...
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Electricity can heal wounds three times as fast (2023)
Chronic wounds are a major health problem for diabetic patients and the elderly – in extreme cases they can even lead to amputation. Using electric stimulation, researchers in a project at Chalmers University of Technology, Sweden, and the University of Freiburg, Germany, have developed a method that speeds up the…
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Getting a paper accepted
Page 1 Accepts, the Rest Avoids Rejection
173
10 Years of Pomological Watercolors
A decade ago today I published a blog post calling for the US government to release its paintings of fruits. The Pomological Watercolor Collection, as I had recently come to know, is a beautiful and remarkable corpus of over 7,000 pictures of fruits and other biological specimens, made between the 1880s and 1940s…
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The contrarian physics podcast subculture
This is the story of how a circle of popular science communicators, who built their brands on championing free inquiry, worked to suppress scientific critique. Of how Eric Weinstein, the man who co…
175
New research reveals longevity gains slowing, life expectancy of 100 unlikely
A new study co-authored by a University of Wisconsin–Madison professor finds that life expectancy gains made by high-income countries in the first half of the 20th century have slowed significantly, and that none of the generations born after 1939 will reach 100 years of age on average. Published in the journal…
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Lead is still bad for your brain
Wait, wasn't this solved by the Romans? Anyway, my grandma ate lead paint and she was totally fine.
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Beetroot juice lowers blood pressure by changing oral microbiome: study
The blood pressure lowering effect of nitrate-rich beetroot juice in older people may be due to specific changes in their oral microbiome, according to the largest study of its kind. Researchers at the University of
178
Dopamine signals when a fear can be forgotten
Study shows how a dopamine circuit between two brain regions enables mice to extinguish fear after a peril has passed.
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100 Years to Solve an Integral (2020)
The integral of sec(x) is well known to any beginners calculus student. Yet this integral was once a major outstanding maths problem. It was first introduced...
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In Search of AI Psychosis
Folie a deux ex machina