1231
Mapping the off-target effects of every FDA-approved drug in existence
6.2k words, 29 minutes reading time
New
The latest blog posts to take off on Hacker News. 6,220 posts.
1232
HTTPS by default
One year from now, with the release of Chrome 154 in October 2026, we will change the default settings of Chrome to enable “Always Use Secure Connections”. This means Ch…
1233
What we talk about when we talk about sideloading
We recently published a blog post with our reaction to the new Google Developer Program and how it impacts your freedom to use the devices that you own in th...
1234
Springs and bounces in native CSS
The “linear()” timing function is a game-changer; it allows us to model physics-based motion right in vanilla CSS! That said, there are some limitations and quirks to be aware of. I’ve been experimenting with this API for a while now, and in this post, I’ll share all of the tips and tricks I’ve learned for using it…
1235
Cancer survival rates are misleading
UPDATE: I submitted a more formal version of this article to the UMAP Journal (Undergraduate Mathematics and Its Applications), which publishes articles that use mathematical modeling for real-world problems, often with a pedagogical or expository angle. A preprint is available on arXiv at…
1236
I've been loving Claude Code on the web
It’s very much a “v1” product. You type a prompt to start a new thread, it launches a little container for your agent to work in, and you can keep talking to it. It produces a branch, which you can open a PR for (that’s the only way to see a diff of the changes Claude Code made, for now). Or if you want to keep…
1237
Why does Swiss cheese have holes?
Swiss cheese gets holes from carbon dioxide bubbles during the cheese-making process. Learn more about what causes the holes in Swiss cheese at U.S. Dairy.
1238
The human only public license
A copyleft software license that restricts AI usage
1239
The decline of deviance
Where has all the weirdness gone?
1240
How to build a 747 – A WorldFlight Story
How far would you go for realism? The world of flight simulation has come a long way over the past […]
1241
The AirPods Pro 3 flight problem
Testing Apple’s latest noise-cancelling earbuds at 39,000 feet reveals a potential flaw most users won’t notice, until they fly.
1242
Asus Announces October Availability of ProArt Display 8K PA32KCX
ProArt Display 8K PA32KCX arrives in October! Experience 8K HDR with mini LED, 4032-zone dimming, 1200 nits brightness, built-in colorimeter & Thunderbolt 4. Perfect for creators. Subscribe to ASUS Pressroom for the latest tech updates!
1243
Our LLM-controlled office robot can't pass butter
Can LLMs control robots? We answer this by testing how good models are at passing the butter – or more generally, do delivery tasks in a household setting. State of the art models struggle, with the best model scoring 40% at Butter-Bench, compared to 95% for humans.
1244
Ubiquiti SFP Wizard
Celebrate SFP Liberation Day with Ubiquiti’s new SFP Wizard, the $49 portable tool that tests and programs any SFP or QSFP module in seconds. Enjoy up to 1000% off Ubiquiti SFPs and unlock true universal compatibility across every switch and network.
1245
The next chapter of the Microsoft–OpenAI partnership
Microsoft and OpenAI sign a new agreement that strengthens its long-term partnership, expands innovation, and ensures responsible AI progress.
1246
Tailscale Services
Tailscale Services is a new way to define available resources on your network and expand the granularity of your access controls to resources that may not have Tailscale installed on them.
1247
We need a clearer framework for AI-assisted contributions to open source
A framework for reasoning about AI-based changes you encounter or create.
1248
Understanding the Worst .NET Vulnerability
In this post I discuss request smuggling, the recent vulnerability in ASP.NET Core with a severity score of 9.9, and how attackers could exploit it
1249
Criminal complaint against facial recognition company Clearview AI
Clearview AI is known for scraping billions of photos of people around the world on the internet – and selling its facial recognition system to law enforcement and state actors
1250
I built the same app 10 times: Evaluating frameworks for mobile performance
I needed to choose a framework for a mobile-first app at work. I started comparing Next.js, SolidStart, and SvelteKit, then expanded to 10 frameworks. The measurements revealed dramatic differences in bundle sizes, performance, and the real cost of framework choices.
1251
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Quantifying pass-by-value overhead
Owen's personal website and portfolio
1253
AI can code, but it can't build software
AI can write code, but it can’t build real software. Software engineering remains human work because AI can code, not engineer.
1254
Iroh-blobs
Learn about the new features in the new blobs API
1255
Linux VM without VM software – User Mode Linux
Quick demonstration of using User Mode Linux (UML) to run a Linux VM inside Linux's userspace, without additional VM software or even root permissions
1256
Welcome to hell; please drive carefully
A while back we watched a video on the topic of British road crossings (which I strongly recommend, as well as Chris's shorter video specifically about Zebra crossings ) and since then Tess has been calling out the different crossings by their proper animal names. This explains why, with tickets to a Halloween event…
1257
The PSF has withdrawn a $1.5M proposal to US Government grant program
The Python Software Foundation was recently "recommended for funding" (NSF terminology) for a $1.5m grant from the US government National Science Foundation to help improve the security of the Python …
1258
Creating an all-weather driver
Life doesn't freeze when winter comes—if anything, that's when riders need reliable transportation most, when being exposed to the elements becomes less appealing. Today, the Waymo Driver successfully navigates rain, fog, sandstorms, and freezing temperatures. As we expand to more cities across the U.S. and globally…
1259
The new calculus of AI-based coding
A collection of posts by Joe Magerramov
1260
Avoid 2:00 and 3:00 am cron jobs (2013)
A word to the wise: Do not set any cron jobs for 2:00 am or 3:00 am on Sunday morning! Or to be safe, on other mornings besides Sunday as well, since jobs originally set to run on some particular day may eventually be changed to run on another day, or every day.