The latest blog posts to take off on Hacker News. 80,802 posts.
Lead optimisation is the step in drug design where you take a molecule that sort of works and try to make it actually work, and it’s arguably the step where most real-world design campaigns succeed or die. Due to the influence of a couple of my pals , I have recently become interested in using machine learning to do…
Dmitry.GR: Fisher-Price Pixter: From unknown and obscure to fully documented, emulated, and preserved
yes, as in singular one. Back in April 2026 Anthropic caused a lot of media noise when they concluded that their new AI model Mythos is dangerously good at finding security flaws in source code. Apparently Mythos was so good at this that Anthropic would not release this model to the public yet but instead … Continue…
I vibe-coded a GPU-aware Kubernetes TUI for 7 months, archived it, and started over. Here's what AI gets wrong when projects grow complex.
I’ll get straight to the point: your AI coding agent, the one you use to write code, needs to reduce your maintenance costs. Not by a little bit, either. You write code twice as quick now? Better hope you’ve halved your maintenance costs. Three times as productive? One third the maintenance costs. Otherwise, you’re…
Experiments with getting usable outputs out of local models on a standard Macbook
Here is a fun thought: if we ask Claude Code to act as a user space IP stack, how quickly will it be able to respond to a ping?
A sophisticated campaign is abusing the Obsidian note-taking app to deliver a new RAT, PHANTOMPULSE, to targets in the finance and crypto sectors using...
A series of unfortunate events.
Local AI models should be the default.
...or welcome back! I’ve been silent for the last 7 years and now I’m trying to resurface with this new blog :-) Some of you might remember my previous work on Qubes OS1, a paranoid-security OS, which I started back in 2009, and led its development for the
10 implementations of handwritten matrix multiplication: from plain C and Swift through to Metal
How wind and solar quietly pushed gas off the margin, and the wholesale price followed.
The one where I suggest finding the nearest lifeboat.
My best piece of travel advice: don't do what the locals do.
Stephen Brennan's personal website and blog.
Note for numberphiles: all numbers have been rounded to their first significant digit, because I’m a fan of Rob Eastaway’s “zequals” method of getting to the point when it comes to estimation. It’s much more valuable to walk away with the heuristic “some dude got a 300x memory reduction by swapping out a database he…
An article about ADHD, Task Paralysis and AI.
Updates to the Gemini API File Search tool makes building efficient, multimodal file retrieval systems easier for developers.
This is what happens when you get arrested in Japan and where you're sent off to will leave you speechless.
Secure Boot protects a system from an attacker that compromises the boot flow. For example, without Secure Boot it is easy to replace the code that reads your disk encryption password and store it somewhere where the attacker can pick it up later. So ideally you want Secure Boot to be enabled to limit the code that…
If you run a server with cPanel or WHM, you need to read this carefully. On May 8, 2026 — just ten days after the cPanel CVE-2026-41940 authentication bypass was used to compromise 44,000 web hosting servers and deploy ransomware — cPanel quietly released a second emergency security patch. This one covers three new…
I don’t like people adding tracking stuff to URLs. Still less do I like people adding tracking stuff to my URLs.
I'm creating a simple developer utility to make managing Claude Code profiles (e.g. running it with DeepSeek, or some OpenRouter models) a little bit easier.
I like the Internet. I am old enough to remember the pre-Internet era and despite the younger generations pining for those simpler days, I was there. Paper maps were absolutely horrible, just you and a compass in your car on the side of the road in the middle of
Thirty years ago, Brewster Kahle founded the Internet Archive with an ambitious goal: Universal Access to All Knowledge. Today, that mission continues to grow with an exciting new chapter: the launch of the Internet Archive Switzerland, a non-profit foundation based in St. Gallen. The Internet Archive Switzerland…
This document contains a set of informal notes on how to build an alternative specification to the Web, in such a way that hopefully prevents many of its drawbacks while still preserves many of the good points. This document is not an specification, and is therefore subject to change over time.
Laurent Le Brun's blog
I was one of the very first advocates for AWS back when it was brand new - SQS, S3, EC2 SimpleDB - it was a lot smaller back then. In fact I...
