Best of 2021

The blog posts Hacker News loved most in 2021. 5,820 posts.

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Why cancer cells waste so much energy

MIT biologists have found a possible explanation for the Warburg effect, first seen in cancer cells in the 1920s. They found cancer cells use fermentation, an inefficient metabolic pathway, because it helps them to generate large quantities of a molecule called NAD+, which they need to synthesize DNA and other…