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Study Reveals Immune Driver of Brain Aging
Scientists have identified a key factor in mental aging and shown that it might be prevented or reversed by fixing a glitch in the immune system's front-line soldiers.
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Alan Kay on the context and catalysts of personal computing
Alan Kay — “father of personal computers" — is best known for his work on personal computing and for leading the team that developed Smalltalk.
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Post-SSRI sexual dysfunction
Post-SSRI sexual dysfunction (PSSD) is a condition in which sexual function does not return to normal after the use of SSRIs and related antidepressants.
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The Highest Forms of Wealth
Wealth is easy to measure but hard to value.
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Learning Ruby: Things I Like, Things I Miss from Python
Thoughts on Ruby from the point of view of a Pythonista, brought to you by Workpath, the strategy execution platform.
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Dabrowski’s theory and existential depression (2020)
When people undergo a great trauma or other unsettling event—they have lost a job or a loved one dies, for example—their understanding of themselves or of
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Multitasking Doesn't Work
When we think we’re multitasking, most often we aren’t really doing two things at once, but instead, individual actions in rapid succession.
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Tor in 2022
It has become a tradition for me to write a blog post at the end of each year, sharing my vision for the Tor Project for the upcoming year. Before talking about what I see for us in 2022, I want to reflect on 2021 and how this has been a year of resilience for Tor.
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Human Rapamycin Longevity Clinical Trials Begin
Today is a doubly important day: it marks the final day of the PEARL campaign and it is a celebration of another victory for the life extension community.
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Pursue High-Quality Leisure
If I stop surfing the Internet, what am I going to do all day?
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Why most non-fiction authors don't make any money
Four royalty-wrecking blunders & how to fix them
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Once an Addict, Always an Addict?
Is an addictive personality a thing? Is an addict’s brain permanently broken?
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Amazon Introduces Re:Post, a “Stack Overflow” for AWS
The internet is an excellent resource for well-intentioned guidance and answers. However, it can sometimes be hard to tell if what you’re reading is, in fact, advice you should follow. Also, some users have a preference toward using a single, trusted online community rather than the open internet to provide them with…
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The Internet Archive transforms access to books in a digital world
In honor of Open Access Week, and particularly this year’s theme of structural equity, we wanted to highlight a project from the Internet Archive that is doing extraordinary work promoting access to knowledge. The bad news: that project is also under legal threat. The good news: the Archive, with...
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Closing email with “thanks” gets the most replies
When you’re drafting an email, ending it is the easiest part. Whether you sign-off with “Warmest Regards,” “Thanks,” or “Keep On Keepin’ On,” it only takes a second, and you probably don’t give it a second thought. Do email closings even matter? And if so, is “best” really best? We looked at closings in over 350,000…
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Having a successful career with depression, anxiety and imposter syndrome
The first half of this conversation is a searingly honest account of...
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Why are our brains shrinking?
As promised, here is the first post in our “The Student of Life” series. This essay, focusing on the fascinating subject of the shrinkage of our brain over the last 70,000 years, was masterfully penned by USF student Savannah Robison during the Fall 2017 semester of BIOL100. It is a wonderful example of student…
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Why it’s usually crazier than you expect
I want to try to explain why Gamestop went up 100-fold in the last year and why Sears never recovered.
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AI Explorables: big ideas in machine learning, simply explained
People + AI Research (PAIR) is a multidisciplinary team at Google that explores the human side of AI.
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Intermittent fasting in mice improves long-term memory retention
Intermittent Fasting is an effective means of improving long term memory retention and generating new adult hippocampal neurons in mice
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Mouse studies show gene therapy can cause big drop in latent herpes infections
Improved gene therapy techniques cleared up to 95 percent of latent herpes virus in mice. Human trials? At least 3 years away. Fred Hutch virologist Dr. Keith Jerome hopes this study "opens up the idea that we can start thinking about cure, rather than just control of the virus."
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New study examines ‘Achilles heel’ of cancer tumours
Ranked among the world’s top medical schools with the fifth-largest MD enrollment in North America, the UBC Faculty of Medicine is a leader in both the science and the practice of medicine. Across British Columbia, more than 12,000 faculty and staff are training the next generation of doctors and health care…
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From macOS to Arch Linux
First impressions
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Palm oil favors tumor expansion
Ninety per cent of cancer deaths are caused by metastasis, that is to say, the spread of the primary tumour to other organs. Scientists led by ICREA researcher Dr. Salvador Aznar-Benitah at IRB Barcelona have described the mechanism by which a diet rich in palmitic acid makes tumour cells more aggressive, conferring…