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Science & Space

The most popular blog posts about science & space on Hacker News. 4,455 posts.

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NeurIPS 2025 Best Paper Awards

The Best Paper Award Committee members were nominated by the Program Chairs and the Database and Benchmark track chairs, who selected leading researchers across machine learning topics. These nominations were approved by the General Chairs and Next Generation and Accessibility Chairs.

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An idiot’s guide to lead optimisation for proteins

Lead optimisation is the step in drug design where you take a molecule that sort of works and try to make it actually work, and it’s arguably the step where most real-world design campaigns succeed or die. Due to the influence of a couple of my pals , I have recently become interested in using machine learning to do…

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The Eclipse via Satellite

Yesterday’s eclipse as seen by the GOES-East weather satellite. I just grabbed the full-disk geocolor JPGs with wget and stitched them together with ffmpeg. BTW, If you’re wondering why the clouds remain in view as night falls to the East, it’s because the geocolor image is a composite of “true color” daytime and a…