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Science & Space

The most popular blog posts about science & space on Hacker News. 422 posts.

2025
192

Student discovers fungus predicted by Albert Hoffman

Making a discovery with the potential for innovative applications in pharmaceutical development, a West Virginia University microbiology student has found a long sought-after fungus that produces effects similar to the semisynthetic drug LSD, which is used to treat conditions like depression, post-traumatic stress…

200

Is Ketamine Neurotoxic?

It is clear that ketamine at a sufficient dose & frequency can and does kill neurons through NMDA-driven excitotoxicity. However, what does a sufficient dose & frequency mean? There is a common myth that ketamine is “neurogenetic”. This is mostly false. While it does increase neurogenesis in the only two places in the…

208

A built-in 'off switch' to stop persistent pain

J. Nicholas Betley has led collaborative research seeking the neural basis of long-term sustained pain and finds that a critical hub in the brainstem holds a mechanism for stopping pain signals from reaching the rest of the brain. Their findings could help clinicians better understand chronic pain and lead to new…