331
Claude discovers a novel enzyme system with CRISPR-like repeats
In early results from our new life sciences research lab, Claude agents found an enzyme system whose function is still unknown.
Topics /
AI & Machine Learning
The most popular blog posts about ai & machine learning on Hacker News. 6,306 posts.
332
Markov Chains Explained Visually (2014)
Markov chains, named after Andrey Markov , are mathematical systems that hop from one "state" (a situation or set of values) to another. For example, if you made a Markov chain model of a baby's behavior, you might include "playing," "eating", "sleeping," and "crying" as states, which together with other behaviors…
333
Gemini: Google's most capable AI model yet
Gemini is our most capable and general model, built to be multimodal and optimized for three different sizes: Ultra, Pro and Nano.
334
Grok 4.5
Grok 4.5 is SpaceXSI's smartest model built for coding, agentic tasks, and knowledge work.
335
Measuring the impact of AI on experienced open-source developer productivity
We conduct a randomized controlled trial to understand how early-2025 AI tools affect the productivity of experienced open-source developers working on their own repositories. Surprisingly, we find that when developers use AI tools, they take 19% longer than without—AI makes them slower.
336
Claude Fable is relentlessly proactive
After two days of experience with Claude Fable 5 I think the best way to describe it is relentlessly proactive. It knows a whole lot of tricks and it will …
337
338
Reflections on OpenAI
I wanted to share my reflections because there's a lot of smoke and noise around what OpenAI is doing, but not a lot of first-hand accounts of what the culture of working there actually feels like .
339
Dots: Always-on agents
Dots by OpenAI are proactive assistants that can keep working across complex projects and everyday tasks. Learn how dots help you stay in control while work moves forward.
340
Where's the shovelware? Why AI coding claims don't add up
78% of developers claim AI makes them more productive. 14% say it's a 10x improvement. So where's the flood of new software? Turns out those productivity claims are bullshit.
341
Stable Diffusion Public Release
We are delighted to announce the public release of Stable Diffusion and the launch of DreamStudio Lite.
342
Voxtral 3
Voxtral 3: Mistral's voice agent SDK for real-time speech in 50+ languages, accurate transcription, emotional TTS, deep tool use.
343
How to Write with an LLM
Two rules keep an LLM from pasteurizing your writing: never take a word it suggests, and never let it encourage you. Then hand it all the tedious work.
344
An AI agent published a hit piece on me – more things have happened
Context: An AI agent of unknown ownership autonomously wrote and published a personalized hit piece about me after I rejected its code, attempting to damage my reputation and shame me into acceptin…
345
Google Antigravity exfiltrates data via indirect prompt injection attack
An indirect prompt injection in an implementation blog can manipulate Antigravity to invoke a malicious browser subagent in order to steal credentials and sensitive code from a user’s IDE.
346
GitHub Copilot is moving to usage-based billing
Starting June 1, your Copilot usage will consume GitHub AI Credits.
347
Run DeepSeek R1 Dynamic 1.58-bit
DeepSeek R-1 is the most powerful open-source reasoning model that performs on par with OpenAI's o1 model. Run the 1.58-bit Dynamic GGUF version by Unsloth.
348
So you want to use OpenRouter?
Might seem simple on the face of it, but unfortunately it's pain all the way down.
349
Qwen3-Coder: Agentic coding in the world
GITHUB HUGGING FACE MODELSCOPE DISCORD Today, we’re announcing Qwen3-Coder, our most agentic code model to date. Qwen3-Coder is available in multiple sizes, but we’re excited to introduce its most powerful variant first: Qwen3-Coder-480B-A35B-Instruct — a 480B-parameter Mixture-of-Experts model with 35B active…
350
The First Rule of Machine Learning: Start Without Machine Learning
Why this is the first rule, some baseline heuristics, and when to move on to machine learning.
351
Structured Outputs in the API
We are introducing Structured Outputs in the API—model outputs now reliably adhere to developer-supplied JSON Schemas.
352
GPT-4 API General Availability
GPT-3.5 Turbo, DALL·E and Whisper APIs are also generally available, and we are releasing a deprecation plan for older models of the Completions API, which will retire at the beginning of 2024.
353
The Google Willow Thing
Yesterday I arrived in Santa Clara for the Q2B (Quantum 2 Business) conference, which starts this morning, and where I’ll be speaking Thursday on “Quantum Algorithms in 2024: How Should…
354
Building Effective "Agents"
Practical guidance from Anthropic on building reliable AI agents, from simple composable patterns to fully autonomous systems.
355
GPT‑6 and Intelligent UI for everyone
GPT‑6 is rolling out globally in ChatGPT with Intelligent UI, delivering faster responses with visuals and interactive experiences you can explore and use directly.
356
Gemini 3.6 Flash, 3.5 Flash-Lite, and 3.5 Flash Cyber
We’re introducing new Gemini models, including Gemini 3.6 Flash, 3.5 Flash-Lite and 3.5 Flash Cyber.
357
Claude Code daily benchmarks for degradation tracking
Track Claude Code's daily performance on SWE-Bench-Pro as we collect an Opus 5.5/high baseline.
358
Vibe code is legacy code
Code that nobody understands is tech debt
359
On being listed as an artist whose work was used to train Midjourney
I’ve had Feeling Hard Or Hardly Feeling saved to my hard drive since 7-17-2005 without even knowing who made it. Just now bothered to find out.
360
Replacing my best friends with an LLM trained on 500k group chat messages
An exploration into customizing LLMs for personal use