Top posts

Every blog post that took off on Hacker News, ranked by the votes of its best submission. 4,457 posts.

Science & Space
Any year
3853

The Breeder's Equation

R is the response to selection, S is the selection differential, and h 2 is the narrow-sense heritability. This is the workhorse equation for quantitative genetics. The selective differential S, is the difference between the population average and the average of the parental population (some subset of the total…

3854

How far behind a plane is its noise?

If you’re ever near a relatively low flying airplane, you may have noticed that it sounds like it’s in a different spot in the sky than where it actually is. You can hear the loud engines, and your ears tell you it should be in one place, but your eyes tell you it’s clearly well ahead of its noise. It’s a funny visual…

3858

How Correlated Are You?

This post is an offshoot from Chapter 1 of Probably Overthinking It, which is available for pre-order now! Suppose you measure the arm and leg lengths of 4082 people. You would expect those measurements to be correlated, and you would be right. In the ANSUR-II dataset, among male members of the armed forces, this…

3862

CRISPR Gene Editing

CRISPR is a recently discovered genomic tool that could potentially revolutionize genetic modification and editing, including gene silencing, editing, activating, and other crucial functions. It has made a big splash in the synthetic biology community, and mentions of CRISPR have started cropping up elsewhere in the…

3863

Analyzing my DNA

I recently bought 23andme [http://23andme.com], a service which requires you to send off a DNA sample, and in return performs a series of interesting tests concerning your health and ancestry. I bought the test as a birthday present to myself, somewhat because I was interested in the results,

3867

Synthetic Cartilage (2020)

The thin, slippery layer of cartilage between the bones in the knee is magical stuff: strong enough to withstand a person’s weight, but soft and supple enough to cushion the joint against impact, over decades of repeat use. That combination of soft-yet-strong has been hard to reproduce in the lab. But now, Duke…