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Every blog post that took off on Hacker News, ranked by the votes of its best submission. 2,419 posts.

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2109

The Breeder's Equation

R is the response to selection, S is the selection differential, and h 2 is the narrow-sense heritability. This is the workhorse equation for quantitative genetics. The selective differential S, is the difference between the population average and the average of the parental population (some subset of the total…

2113

Synthetic Cartilage (2020)

The thin, slippery layer of cartilage between the bones in the knee is magical stuff: strong enough to withstand a person’s weight, but soft and supple enough to cushion the joint against impact, over decades of repeat use. That combination of soft-yet-strong has been hard to reproduce in the lab. But now, Duke…