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New antibiotic targets IBD and AI predicted how it would work
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The latest blog posts to take off on Hacker News. 1,227 posts.
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Sora Update #1
We have been learning quickly from how people are using Sora and taking feedback from users, rightsholders, and other interested groups. We of course spent a lot of time discussing this before...
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How does gradient descent work?
This is the companion website for the paper Understanding Optimization in Deep Learning with Central Flows , published at ICLR 2025.
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OpenAI Is Just Another Boring, Desperate AI Startup
What is OpenAI? I realize you might say "a foundation model lab" or "the company that runs ChatGPT," but that doesn't really give the full picture of everything it’s promised, or claimed, or leaked that it was or would be. No, really, if you believe its leaks to
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Who needs Git when you have 1M context windows?
Lately I’ve heard a lot of stories of AI accidentally deleting entire codebases or wiping production databases . But in my case it was the other way around. I removed some working code and the LLM helped me to recover it.
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Which table format do LLMs understand best?
We benchmarked 11 data formats, including markdown tables, JSON, CSV, YAML, XML, and more, to see which LLMs understand best. We found surprising accuracy and token cost trade-offs.
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What makes 5% of AI agents work in production?
Beyond the Prompt: Notes from the Context Frontier
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Email immutability matters more in a world with AI
Email immutability matters even more in a world of AI. Here is how we enable your use of your data, in line with our values.
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How the AI Bubble Will Pop
The artificial intelligence boom is the most important economic story in the world. But the numbers just don't add up.
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Announcing Tinker
Introducing Tinker: a flexible API for fine-tuning language models.
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The RAG Obituary: Killed by agents, buried by context windows
I’ve been working in AI and search for a decade. First, I built Doctrine, the largest European legal search engine, and now I am building Fintool , an AI-powered financial research platform that helps institutional investors analyze companies, screen stocks, and make investment decisions.
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Fossabot: AI code review for Dependabot/Renovate on breaking changes and impacts
Announcing fossabot, a new AI Agent for making strategic dependency updates, backed by a comprehensive accuracy, consistency, and correctness framework.
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Building the heap: racking 30 petabytes of hard drives for pretraining
We built the heap, a 30 petabyte data storage cluster in downtown San Francisco, and spent under $500,000.
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Unix philosophy and filesystem access makes Claude Code amazing
Build the advantage your competitors can’t buy2025414 points216 commentsAI & Machine Learning details
If you've talked to me lately about AI, you've almost certainly been subject to a long soliloquy about the wonders of Claude Code. What started as a tool I ran in parallel with other tools to aid coding has turned into my full-fledged agentic operating system, supporting all kinds of workflows.
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Making sure AI serves people and knowledge stays human
Today we’re sharing a human rights impact assessment on AI/ML to help Wikimedia understand effects on human rights.
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Sora 2
This post introduced Sora 2, a video generation model with synchronized dialogue and sound effects. The Sora product is no longer available.
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Cerebras systems raises $1.1B Series G
Cerebras powers the world's fastest AI inference on the biggest wafer chip. Cerebras CS-4 delivers up to 30x faster inference than GPUs.
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Designing agentic loops
Coding agents like Anthropic’s Claude Code and OpenAI’s Codex CLI represent a genuine step change in how useful LLMs can be for producing working code. These agents can now directly …
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Comprehension debt: A ticking time bomb of LLM-generated code
Psst. If your boss won’t invest in training you in Specification By Example (BDD, ATDD), I’m running out-of-hours workshops on May 12 and 16 specifically for self-funding learners. £99 + UK VAT. An…
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Companies are lying about AI layoffs?
Companies are saying that the economy and AI are causing the large amount of tech layoffs, but Vanessa Wingårdh looked at the H-1B visa data and noticed that the companies are lying. She argues that...
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AI tools I wish existed
The models are powerful as is. But where are the tools?
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Effective context engineering for AI agents
In this post, we explore strategies for effectively curating and managing their context.
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LoRA Without Regret
How LoRA matches full training performance more broadly than expected.
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Instant Checkout and the Agentic Commerce Protocol
We’re taking first steps toward agentic commerce in ChatGPT with new ways for people, AI agents, and businesses to shop together.
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Claude Sonnet 4.5
Claude Sonnet 4.5 is the best coding model in the world, strongest model for building complex agents, and best model at using computers.
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ML on Apple ][+
Success! There is machine learning happening on my Apple ][+.
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To AI or not to AI
A two-week experiment building an app with full AI assistance, exploring both the promise and frustrations of LLM-based development workflows.
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We bought the whole GPU, so we're damn well going to use the whole GPU
Benjamin Spector* , Jordan Juravsky* , Stuart Sul* , Dylan Lim , Owen Dugan , Simran Arora , Chris Ré
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The AI coding trap
If you ever watch someone “coding”, you might see them spending far more time staring into space than typing on their keyboard.