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The Sloppification of Peptides
Nobody in the comments is real
New
The latest blog posts to take off on Hacker News. 3,699 posts.
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Tragically, as many as 9625 out of every 10k individuals may be neurotypical
Neurotypical syndrome is a neurobiological disorder characterized by preoccupation with social concerns, delusions of superiority, and obsession with conformity.
873
JIT Compiling Code in 5μs
Build a copy-and-patch JIT compiler in Rust, generate ARM64 machine code, and benchmark it against an interpreter and handwritten implementation.
874
The End of an Athlon
When I was researching the mess related to strange and poorly documented CPUID bits in the Athlon MP and XP processors , I had to swap a lot of CPUs. This was uneventful in most cases… but only most.
875
Fast and Hard Code
People pick languages differently with LLMs.
876
To become a better writer, read as much as you can
I’m obsessed with the craft of writing. I write every day, I read about the craft often, and in my...
877
I dream of quieter computing
A quick note about future of computing and indieweb. It's about a 2 minute read.
878
AI Chip Architectures
A look at AI Chip Architectures. NVIDIA, AMD, TPUs, Trainium, Groq, Cerebras.
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hdiutil is deprecated in macOS 27 Golden Gate
The macOS command-line tool hdiutil is used to manipulate disk images. From the WHAT'S NEW section of man hdiutil on the latest macOS 27 Golden Gate beta:
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Things I want in a modern relational query language
This was a very old draft I’ve had sitting around for years. The recent discussions of new query languages like Acadia spurred me to revisit, revise, and publish this. I think one of the biggest causes of NoSQL is that… Continue reading →
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A Kantian Critique of "Sorry" by Justin Bieber
Justin Bieber's "Sorry" is a song about regret, asking for forgiveness, and wanting another chance after having hurt someone. But philosophically speaking, what exactly makes an apology morally meaningful?
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There's no reason for software to be slow anymore
The other day, I saw a viral tweet saying that people talking about how LLMs are causing slow, bloated, code are going to eat crow once they re-write everything in super-optimized assembly. We're not quite at the point where we want to write everything in assembly , but some variant of what Nolan Lawson said about…
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Three important steps in my maturation process
My father passed recently, and he was twice my age. I am approximately the same age that he was when I was born, and I am now “the old generation” - there’s no one left in the generation above me.
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A week of using Codex more than Claude
Claude goes above and beyond what is asked and guesses what you might want. Codex does what you tell it and stops at the first sign that it might be done. Ten impressions from a week of using Codex more.
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One night in Uzbekistan: Why was this one data point so influential?
We have a comment coming out in Nature next week that is going to cause the retraction of a high-profile paper by Kotz et al. from last year (the second most cited climate paper in the news in 2024).
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OTel isn’t going well
For years now one of the most reliable complaints I hear when I try to drag a team off their vendor specific SDK and onto OpenTelemetry is some variation of: "why does it seem like this isn't done yet?" Vendor SDKs for observability are, to put it charitably, idiot-
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Building an (almost) fully self-hosted, sandboxed, agentic software factory
I built an (almost) fully self-hosted, sandboxed, agentic software factory.
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I Just Want to Search
Learning to search was a key skill growing up as a teen in the 2000s. How to use accurate keywords, quotes, the entire lot of search operators. Google-fu was a hard earned skill (yes, I read a book) and helped me figure out a surprising amount of life.
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I ran Photoshop on a £0.60 computer chip
Colin's things that might be useful or interesting2026154 points49 commentsHardware & Electronics details
I've always had a fascination with simpler and low power computing. This lead me to run Photoshop on a 60 pence computer chip and it amazes me that this is possible.
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Zig’s Io.Threaded is neat
std.Io.Threaded is one of the implementations of Zig's new Io interface that enables concurrency. This is a boring just use threads impl. I personally find it neat though --- it does this weird thing that I wanted to do for ages, that to my knowledge no one else is doing properly, and implements it better than I…
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I accidentally logged hundreds of thousands of phone calls to military bases
How an expired nameserver let me take over e164.arpa zones for multiple territories, and why I probably should have checked my logs sooner.
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New Worlds: We are living in the future of J.G. Ballard or William Gibson
Don’t let the absence of a flying car in your garage distract you: we are definitely now living in a version of the future out of J.G. Ballard or William Gibson. Every day I notice a news story tha…
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I'm becoming AI-blind
Recently I've been catching myself having these little moments at work, when I'm trying to read a document someone has sent me and my brain somehow refuses to analyze it. It feels like I'm reading it, but I'm unable to focus on its content. I sat down to analyze these situations and realized they all have a common…
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Stop Making TUIs
It's time to stop drawing user interfaces with punctuation characters. Native UI is a completely solved problem.
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It is a sign of the times that Amazon gets to call this fair use
This 404 report justly been getting considerable coverage. Amazon is buying massive quantities of books, scanning them for AI training dat...
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Aaron Swartz was prosecuted for scraping, while Meta does it without consequence
Also here's a cool unrelated photo of a chipmunk because I need some chill
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Stop eating Lady Gaga's Oreos
OR: The Great Switcheroo
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SpacetimeDB: a short technical review
This blog post has been archived! SpacetimeDB has improved a lot since I initially published this technical review, and most of the technical details in it no longer apply.